Journal of Current Glaucoma Practice

Register      Login

VOLUME 11 , ISSUE 2 ( May-August, 2017 ) > List of Articles

ORIGINAL REASEARCH

Neovascular Glaucoma: A Retrospective Review from a Tertiary Eye Care Center in Mexico

Gabriel Lazcano-Gomez, Jeffrey R Soohoo, Anne Lynch, Levi N Bonell, Karina Martinez, Mauricio Turati, Roberto Gonzalez-Salinas, Jesus Jimenez-Roman, Malik Y Kahook

Citation Information : Lazcano-Gomez G, Soohoo JR, Lynch A, Bonell LN, Martinez K, Turati M, Gonzalez-Salinas R, Jimenez-Roman J, Kahook MY. Neovascular Glaucoma: A Retrospective Review from a Tertiary Eye Care Center in Mexico. J Curr Glaucoma Pract 2017; 11 (2):48-51.

DOI: 10.5005/jp-journals-10028-1222

License: CC BY 3.0

Published Online: 01-01-2015

Copyright Statement:  Copyright © 2017; The Author(s).


Abstract

Aim

To describe the demographic characteristics, ocular comorbidities, and clinical outcomes of patients with neovascular glaucoma (NVG) and to determine the number of patients who returned for a follow-up eye examination.

Materials and methods

We examined the clinical data of patients with NVG, who attended a glaucoma clinic between July 2010 and November 2014. We collected information on the demographic characteristics of the patients to include the level of education, ocular comorbidities, NVG stage, visual acuity, glaucoma medications, intraocular pressure (IOP), and the number of patients who had a follow-up ocular examination at month 1, 3, 6, and 12.

Results

Data from 350 patients (473 eyes) with NVG were collected. We found 91% of the cohort had proliferative diabetic retinopathy (PDR). We found blindness in both or one eye in 14% and 31% of the cohort respectively. Low vision was found in both or one eye in 14% and 32% of the eyes respectively. By 6 months follow-up, only 32% of the patients were seen at our clinic and by 12 months follow-up, this number decreased to 15%. Around 60% of the patients were on no IOP lowering drugs at the first visit. We found 53% of the cohort had an incomplete elementary school education.

Conclusion

The results suggest that advanced NVG is a significant ocular problem for patients referred to our clinic with just over half of the patients presenting as blind. We also found that several socioeconomic factors that had an important role in the development of PDR and NVG, specifically, educational status.

Clinical significance

We described the characteristics of a large cohort of patients with very advanced NVG, reflecting the fact that the strict control of the underlying disease must be the main goal of the Mexican national health system.

How to cite this article

Lazcano-Gomez G, Soohoo JR, Lynch A, Bonell LN, Martinez K, Turati M, Gonzalez-Salinas R, Jimenez-Roman J, Kahook MY. Neovascular Glaucoma: A Retrospective Review from a Tertiary Eye Care Center in Mexico. J Curr Glaucoma Pract 2017;11(2):48-51.


HTML PDF Share
  1. Neovascular glaucoma complicating carotid-cavernous fistula. Arch Ophthalmol 1963 Mar;69:304-307.
  2. Neovascular glaucoma. Prog Retin Eye Res 2007 Sep;26(5):470-485.
  3. Outcomes of treatment of neovascular glaucoma with intravitreal bevacizumab. Br J Ophthalmol 2009 May;93(5):589-593.
  4. Intravitreal bevacizumab (Avastin) in the treatment of neovascular glaucoma. Am J Ophthalmol 2006 Dec;142(6):1054-1056.
  5. Intravitreal bevacizumab in a patient with neovascular glaucoma. Ophthalmic Surg Lasers Imaging 2006 Mar-Apr;37(2):144-146.
  6. Intravitreal bevacizumab combined with panretinal photocoagulation in the treatment of open angle neovascular glaucoma. Eur J Ophthal 2009 Nov-Dec;19(6):1028-1033.
  7. Combination intravitreal bevacizumab/panretinal photocoagulation versus panretinal photocoagulation alone in the treatment of neovascular glaucoma. Retina 2008 May;28(5):696-702.
  8. Neovascular glaucoma. Etiologic considerations. Ophthalmology 1984 Apr;91(4):315-320.
  9. Neovascular glaucoma: a retrospective review from a tertiary center in China. BMC Ophthalmol 2016 Jan 27;16:14.
  10. Is the risk of diabetic retinopathy greater in non-Hispanic blacks and Mexican Americans than in non-Hispanic whites with type 2 diabetes? A U.S. population study. Diabetes Care1998 Aug;21(8):1230-1235.
  11. Aflibercept for the treatment of neovascular glaucoma. Clin Exp Ophthalmol 2015 Dec;43(9):803-807.
  12. [Internet] Report prepared for the International Council of Ophthalmology at the 29th International Congress of Ophthalmology Sydney, Australia, April 2002. [cited 2016, Aug 22] p. 7. Available from: http://www.icoph.org/downloads/visualstandardsreport.pdf
  13. Ten emerging trends in the epidemiology of diabetic retinopathy. Ophthalmic Epidemiol 2016 Aug;23(4):209-222.
  14. Neovascular glaucoma and ocular ischemic syndrome. J Glaucoma 2000 Oct;9(5):409-412.
  15. Diabetic retinopathy. Screening and prevention of blindness. A doctoral thesis. Acta Ophthalmol Scand (Suppl) 1997;(223):1-76.
  16. Serum lipids and proliferative diabetic retinopathy and macular edema in persons with long-term type 1 diabetes mellitus: the wisconsin epidemiologic study of diabetic retinopathy. JAMA Ophthalmol 2015 May;133(5):503-510.
  17. Prevalence of diabetes mellitus and diabetic retinopathy in Filipino vs Caucasian Americans: a retrospective cross sectional epidemiologic study of two convenience samples.Ethn Dis 2012 Autumn;22(4):459-465.
  18. United Kingdom national ophthalmology database study: diabetic retinopathy; report 1: prevalence of centre-involving diabetic macular oedema and other grades of maculopathy and retinopathy in hospital eye services. Eye (Lond) 2013 Dec;27(12):1397-404.
  19. Four-year incidence and progression of diabetic retinopathy and macular edema: the Los Angeles Latino Eye Study. Am J Ophthalmol 2010 May;149(5):752-761.
  20. De que mueren los mexicanos? [Internet] [cited 2016, Aug 24]. Available from: http://www.inegi.org.mx .
  21. High prevalence of diabetic retinopathy and lack of association with integrin α2 gene polymorphisms in patients with type 2 diabetes from Northeastern Mexico. Exp Ther Med 2015 Aug;10(2):435-444.
  22. Opportunities for involving men and families in chronic disease management: a qualitative study from Chiapas, Mexico. BMC Public Health 2015 Oct 5;15:1019.
  23. Prevalence of prediabetes based on fasting plasma glucose and glycosylated hemoglobin in an at-risk Mexican population. Metab Syndr Relat Disord 2015 Oct;13(8):352-355.
  24. Diabetic retinopathy in Mexico. Prevalence and clinical characteristics. Arch Med Res 1994 Autumn;25(3):355-360.
  25. Available from: http://www.inegi.org.mx/est/contenidos/proyectos/encuestas/hogares/especiales/ei2015/default.aspx.
  26. Diabetes and diabetic retinopathy in a Mexican-American population: Proyecto VER. Diabetes Care 2001 Jul;24(7):1204-1209.
  27. Direct costs of medical care for patients with type 2 diabetes mellitus in Mexico micro-costing analysis. Rev Panam Salud Pública 2010 Dec;28(10):412-420. (Span).
  28. Evolution of the type 2 diabetes mellitus epidemia in insured population at the IMSS. Rev Med Inst Mex Seguro Soc 2016 Jul-Aug;54(4):490-503. (Span)
  29. [Direct service costs of diabetes mellitus hospitalisations in the Mexican Institute of Social Security]. Gac Sanit 2016 Aug 2. pii:S0213-9111(16)30139-X. (Span)
  30. p. 28. Available from: http://fundacionidea.org.mx/assets/files/Quehacerconladabetes.pdf.
  31. Ocular complications of diabetes mellitus. World J Diabetes 2015 Feb 15;6(1):92-108.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.